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Drug companies are scrambling for the biggest piece of that profitable pie

Weight loss drugs are medications used in obesity to help individuals achieve weight loss by either reducing appetite, increasing feelings of fullness, or interfering with the absorption of nutrients For instance, in March 2023, according to the World Obesity Federation, a UK-based not-for-profit organization, it is estimated that over 4 billion people are expected to be obese by 2035

Incretins have been shown to indirectly affect hepatic and muscle metabolism, specifically through changes in circulating concentrations of insulin and glucagon [31,78,79,80]

The majority of the research has been conducted on rats and mice

Some of the strongest modifiable risk factors include smoking, alcohol use, and chronic pancreatitis

Mozaffarian reports research funding from the National Institutes of Health, Kaiser Permanente Fund at the East Bay Community Foundation, National Association of Chain Drug Stores Foundation, Google Health, and The Rockefeller Foundation