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Clinical trials have demonstrated greater weight loss with these higher doses compared to diabetes-indicated doses, with Wegovy producing average weight reductions of 12-15% of body weight

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GIP Receptor Agonism Attenuates GLP-1 Receptor Agonist Induced Nausea and Emesis in Preclinical Models Glucagon-like peptide-1 receptor (GLP-1R) agonists decrease body weight and improve glycemic control in obesity and diabetes

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