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While these events did not appear to drive discontinuation, the 20.9% rate at the highest dose warrants close monitoring in the broader TRIUMPH program

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However, they are expensive, meaning everyone living with obesity may not have the chance to use them

Stiffness may also develop alongside the inflammation and joint pain that the patient experiences

Staying hydrated is an important part of supporting your overall health while taking these medications

Getting the retatrutide dose right requires understanding what each receptor does, how titration protects you from gastrointestinal distress, and why the clinical trials used the specific escalation schedules they did