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3 Common causes and risk factors for blood clots include inactivity and immobility, injury and surgery, medical conditions (cancer, heart disease, and inflammatory conditions), medications and lifestyle factors including smoking, overweight and being sedentary

In a recent survey of 50 physicians conducted by strategic advisory firm DNB Markets and Back Bay Life Science Advisors, 94% of doctors ranked the benefit-safety profile as one of the most important factors in prescribing a weight loss medication

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The response to this question as I see it can be framed as follows: Which clinical targets are currently evidence-based, and which targets are aspirational

SGLT-2is are lipid soluble drugs with low molecular weight, as indicated by their chemical structures (Figure 3)