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2025;:10.1038/s41584-025-01302-0

What sets Retatrutide apart is its unique ability to engage three receptors simultaneously: GIP (Gastric Inhibitory Polypeptide) receptor GLP-1 (Glucagon-Like Peptide-1) receptor GCG (Glucagon) receptor This puts Retatrutide into a new medication class known as triple agonists

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