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Safety endpoints included the frequency of AEs, clinical laboratory tests, vital signs, electrocardiogram measurements and psychiatric evaluations reported through the last study visit

Category 2 preparations, made in ISO-classified cleanrooms with stricter environmental controls, can receive longer BUDs of up to 60 days refrigerated or even longer with stability testing data

If shedding appears excessive, laboratory testing for iron stores, vitamin D levels, and thyroid function may be appropriate

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