how do glp-1 receptor agonists work Understanding and their impact on drug discovery Frontiers | GLP−1 receptor agonists
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Glossary CKD Chronic kidney disease CVD Cardiovascular disease FDA Food and Drug Administration GLP-1 Glucagon-like peptide-1 GLP-1s Glucagon-like peptide-1 receptor agonists HF Heart failure MASH Metabolic dysfunction-associated steatohepatitis OA Osteoarthritis OSA Obstructive sleep apnea PAD Peripheral arterial disease SC Subcutaneous T2DM Type 2 diabetes mellitus U.S

doi: 10.1210/en.2009-1510

doi: 10.1056/NEJMoa1612917 41 HernandezAFGreenJBJanmohamedSD'AgostinoRBGrangerCBJonesNPet al

Effects of glucagon-like peptide-1 receptor agonists on major cardiovascular events in patients with Type 2 diabetes mellitus with or without established cardiovascular disease: a meta-analysis of randomized controlled trials

The role of genetic susceptibility continues to be explored in pediatric MASLD

It is also critical in building and maintaining muscle mass
