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Supporting this shift intentionally accelerates the dietary quality improvements that the medication makes easier to achieve

These drugs have demonstrated significant clinical efficacy, especially when combined with lifestyle interventions

The authors note: In conclusion, initiation of GLP-1RA therapy, compared with other active antidiabetic treatments, was associated with a small but statistically significant increase in fracture risk among older adults with type 2 diabetes. Why Might GLP-1 Drugs Affect Bone Density

Glucagon-like peptide (GLP)-1 regulation of lipid and lipoprotein metabolism

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Reviewing studies where people using the drug had been asked about their food cravings and preferences, researchers showed that there was an overall lower desire for dairy and starchy foods, and salty and spicy foods, and also that they wanted a lower number of foods, particularly high-fat, non-sweet foods