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In pooled randomized trials, the risk difference in congenital anomaly rates between letrozole and clomiphene was essentially zero (RD ~0.0, 95% CI spanning no effect) [17]

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doi: 10.1016/j.neulet.2007.01.007

Gomez-Arbelaez D, Bellido D, Castro AI, Ordoez-Mayan L, Carreira J, Galban C, et al

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