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This review summarizes our current knowledge on bone metabolism in PwO treated by GLP-1Ra

Mounjaro (Tirzepatide): Dual GLP-1 & GIP receptor agonist originally approved for type 2 diabetes, now widely used for medical weight loss

Hypoglycemia : While semaglutide does not directly lower blood sugar, it can increase the risk of hypoglycemia, particularly in patients with diabetes on insulin or other medications

Last week (27 June) the Department of Health and Social Care (DHSC) issued a Tier 3 (high impact) medicine supply notification for GLP-1 receptor agonists used in the management of type 2 diabetes

Amylin is a hormone co-secreted with insulin by pancreatic beta cells , where it contributes to physiological processes associated with food intake, gastric emptying, and glucagon signaling

One double-blind, placebo-controlled study showed that GLP-1 can decrease aldosterone secretion in healthy individuals suggesting that GLP-1 can act on blood pressure and the reninangiotensinaldosterone system [93]