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MAbs 7 , 483493 (2015)

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Gallbladder Problems (1.4%) Gallbladder issues including gallstones (cholelithiasis) and gallbladder inflammation (cholecystitis) occurred in 1.4% of participants

Vials are cheap to manufacture but fiddly to use: dosing errors are common, and most patients wont self-inject from one
Understanding those interactions is not optional
