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Yet, when you take a GLP-1 medication, two things happen that may contribute to side effects

Zepbound is the same medication approved specifically for chronic weight management in adults with obesity or overweight with a weight-related condition

Chronic treatment of exendin-4 affects cell proliferation and neuroblast differentiation in the adult mouse hippocampal dentate gyrus

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Further effects are an increase of the net blood brain clearance and the brain metabolism, but it is not known whether they depend on the prevailing plasma glucose (PG) 6

If you want appetite support Glucomannan provides the most appetite-related benefit due to its extreme water-holding capacity