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Seven states

The 12 mg group lost an average of 24.2% body weight at 48 weeks versus 22.8% in the 8 mg group, a difference of 1.4 percentage points

Conclusion GLP-1 pills offer a valuable alternative for patients who resist injections or prefer daily oral medication routines

Retatrutide mimics ghrelin and leptin, which regulate hunger and energy

Common side effects include: Nausea, especially in the early weeks Occasional vomiting or diarrhea Fatigue or mild headaches Redness or discomfort at the injection site Less common but more serious risks include: Pancreatitis Gallbladder issues Kidney concerns in patients with pre-existing conditions The key to safe treatment is proactive monitoring

This results in higher levels of satiation, increased levels of fullness, and a reduced tendency to overeat