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The dual-pathway approach of tirzepatide may produce stronger appetite suppression and weight loss in some individuals, particularly those who've plateaued on GLP-1 monotherapy

Stevens recommends it for patients who are not obese and have tight skin, as skin laxity can sometimes be mistaken for cellulite

If it helps get you to a healthier BMI, then great

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Raul Rodriguez whether one is better for their health goals

A well-studied GIPR missense variant, E354Q (rs1800437), is associated with reduced BMI in large-scale GWAS and Mendelian randomization analyses
