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Description
Losing too much of it may compromise metabolic flexibility and longevity
P9 strongly induces IL-6 expression, which in turn dose-dependently increases GLP-1 secretion from L cells
The Look AHEAD trial showed that intensive lifestyle intervention with behavioral support produced sustained improvements in cardiovascular risk factors
Research on a human model indicated that Scabra extracts (100 mg/kg) reduced glucose levels in db/db mice during the oral glucose tolerance test (OGTT) while plasma GLP-1 and insulin levels significantly rose 10 min post-administration [33]
The bottom line GLP-1 drugs are not a replacement for insulin, and they are not officially approved for T1D (outside of the new 2026 ADA recommendation for T1D with obesity)
We used these data to perform comparisons with the self-report survey data
