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Comprehensive alpha, beta and delta cell transcriptomes reveal that ghrelin selectively activates delta cells and promotes somatostatin release from pancreatic islets

5.1 Limitations Most of the studies yet performed regarding SID and SIH employed observational designs, and data derived from randomised controlled clinical studies are lacking

Eder, L., Thavaneswaran, A., Chandran, V., Cook, R

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In addition, to best serve survival, energy homoeostasis is directly regulated by overlapping neuronal and hormonal signalling that alters appetite, food craving and foraging behaviour to balance short-term fluctuations in energy intake