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Therapy should also be considered in those with a compelling need to minimise weight gain or lose weight, because the links between diabetes and obesity are well known

Trial participants experienced different levels of % total body weight loss depending on the dose: Percentage of total body weight loss on retatrutide After 48 weeks , 83% of patients taking 12 mg lost at least 15% of their body weight , compared to just 2% of those who were on a placebo

Standard dosingup to 3,0004,000 mg per day in divided dosesaddresses mild to moderate pain without the gastric irritation risk that NSAIDs carry

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According to the FDA label, if a dose is missed and the next scheduled dose is more than 4 days away, administer the missed dose as soon as possible

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