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Methods PIONEER REAL Switzerland was a 3444-week, multicentre, prospective, non-interventional, single-arm study of adults with T2D nave to injectable glucose-lowering medication who were initiated on oral semaglutide in routine clinical practice

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The drugs have become popular for their significant weight-loss effects, but their high cost has made them inaccessible for many patients.

--- The net cost per patient fell from ~$12,000 annually in 2021 to ~$6,830 in 2025, but utilization grew faster than prices fell

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