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Research progress of GLP-1RAs in the treatment of type 2 diabetes mellitus

It should not be shared with others

LY3437943, a novel triple glucagon, GIP, and GLP-1 receptor agonist for glycemic control and weight loss: from discovery to clinical proof of concept

Potential role for AMP-activated protein kinase in hypoglycemia sensing in the ventromedial hypothalamus

This becomes particularly important since inflammation in people with obesity may reduce blood-brain barrier integrity 28

P =0.18), GLP-1 RA were associated with a significant reduction in the incidence of MACE compared with placebo and pioglitazone, with a non-significant trend towards reduction in DPP-4 inhibitor-controlled studies [100]