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Understanding the Biological Effects of GLP-1 RAs GLP-1 RAs, also known as GLP1-analogs or incretin mimetics, are a class of obesity medications originally developed for the management of type 2 diabetes

All of the major brand-name medications people currently use for weight loss are based on one of two molecules: semaglutide or tirzepatide, and most are self-injected weekly

doi: 10.1016/S0140-6736(10)60590-9

examined racial disparities in medication adherence and treatment results, reporting that Black and South Asian populations may experience differing outcomes to therapies such as semaglutide and tirzepatide [24,25]

346 Future Perspectives This review has attempted to summarise the complexity of the regulation of metabolic homeostasis by discussing the known/speculative actions of the incretin hormones and the metabolic hormones that are produced by the pancreatic islets

Liraglutide and exenatide have been associated with the development of thyroid C-cell tumors in rodents after lifetime exposure at supratherapeutic doses [169]