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This systematic review and meta-analysis aims to update the evidence on the impact of GLP-1 RAs on EGD outcomes, evaluate the effect of concurrent colonoscopy (CLN) on GRC, and assess the influence of different GLP-1 RA agents on GRC

Take-home message: GLP-1 medicines improve MASH through both systemic metabolic effects and direct, liver-specific mechanisms, with LSECs emerging as a central regulatory hub

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