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DeGruttola AK, Low D, Mizoguchi A, Mizoguchi E

GLP-1 therapy has also shown benefit in improving atherothrombosis markers (e.g., inflammation, endothelial dysfunction, clotting in this population

The key polar interactions within the S2 pocket involve the amino acid residues Glu205, Glu206, and Arg125
When the number of SNPs is less than 2, the Wald ratio is a feasible method

Subgroup analysis in patients with positive baseline C-peptide levels showed a more robust reduction of HbA1c (i.e., 0.69-0.83%) on GLP-1RA in this group (56, 57)

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