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A meta-analysis of 45 trials (94,063 participants), including people with type 2 diabetes enrolled in CVOTs, did not reveal an imbalance between use of GLP-1RA and the incidence of benign or malignant thyroid disease [163]

Experts say taste and smell dysfunction doesnt appear to be a common side effect of GLP-1s, which are widely prescribed for weight loss

Ultimately, understanding how GLP-1 therapies fit into the broader diabetes treatment algorithm helps improve outcomes and quality of life for patients

They also retain beneficial properties for the cardiorenal system

Bifidobacterium infantis produces acetate and lactate, two metabolites that serve as fuel for both Akkermansia muciniphila and Clostridium butyricum

The ongoing development of novel agents, including the GLP-1/glucagon dual receptor agonist maxadutide and the exploration of triple receptor agonists, continues to expand treatment options