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Peptide engineering and pharmacokinetic studies : Investigating the effects of lipidation and other peptide modifications on exposure profiles

Although body mass index (BMI) is widely used for its simplicity and utility at the population level, it fails to capture critical clinical aspects, including body composition, fat distribution, metabolic health, and functional impairment

Building on the search conducted for the 2022 pharmacotherapy revision, we conducted a systematic literature review (search dates January 2022 to July 2024), supplemented by relevant trials published through May 2025, to identify studies assessing the efficacy of pharmacotherapy for weight management

Frias In SURMOUNT-2, researchers enrolled 938 adults with a BMI of 27 kg/m 2 or higher, type 2 diabetes and an HbA1c between 7% and 10% who were on a stable diabetes therapy (mean age, 54.2 years

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