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Patients and Interventions/Exposure : New users of semaglutide (n= 613) and liraglutide (n=4,144), which are GLP-1 receptor agonists approved for diabetes, and users of buproprion-naltrexone (n= 654), an Federal Drug Administration (FDA)-approved weight loss agent, which served as active comparator

Weight loss results vary and are not guaranteed

These symptoms are typically mild to moderate and tend to decrease over time as the body adjusts to the medication

Prioritize protein

Many patients begin to see improvements in cravings and energy levels within the first few weeks, leading to steady and noticeable weight loss

Seek support: Encourage patients to connect with support groups, friends, or family members who can help them stay motivated and accountable