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It is a Schedule II Controlled Substance in the United States, meaning it has a high potential for abuse and addiction
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Inflammation activity (sum of hepatocyte ballooning and acinary activity) was dichotomized: mild ( 1 points) or severe ( 2 points) activity 51

[DOI] [PubMed] [Google Scholar] Kieffer T

Even after treating facial volume loss and skin quality, spots like the arms, thighs and stomach can be left with loose or crepey skin

23 Owing to side effects and treatment failures new therapies are needed
