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Pathophysiology of diarrhoea

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By inhibiting alpha-glucosidase enzymes in the small intestine, it slows carbohydrate breakdown and absorption, helping to moderate blood glucose and insulin responses following meals

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Semaglutide (Wegovy, 2.4 mg weekly), STEP-1, 68 weeks: mean weight loss approximately 14.9%

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The combination of reduced intake and improved metabolism creates the gradual downward trend seen after week two

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doi: 10.1210/jc.2008-2808 57 NyuntOCotterillAMArchboldSMWuJYLeongGMVergeCFet al

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