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Description
These medications are long-acting versions of other GLP-1 medications that have been on the market for over a decade such as liraglutide (Victoza, Saxenda), dulaglutide (Trulicity) or exenatide (Byetta, Bydureon)

These include furosemide, thiazide diuretics, and ritodrine, as GLP-1 usage can decrease their effectiveness, primarily due to delayed absorption.7 Semaglutide medications may also impact thyroid function by increasing serum levothyroxine.7 All GLP-1 medications are a known risk factor for acute pancreatitis.16 While research is limited, there is concern that GLP-1s may contribute to the onset, maintenance, or worsening of disordered eating behaviors
Whether it's being degraded in the gastric acid, or prematurely being activated in the stomach and not absorbed in the small intestine due to delayed gastric emptying from GLP-1 therapies

While the drug is approved by the Food and Drug Administrationand routinely prescribedfor the treatment of ADHD, it's also become popular among people looking to lose weight
Clinical observations suggest semaglutide may reduce migraines through weight loss, reduced inflammation, and GLP-1 receptor effects on pain pathways

GLP-1 modulates fat browning Adipose tissue is produced by the aggregation of a large number of fat cells
