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Based on the annualized event rates in the semaglutide and placebo groups, the SOUL trial was calculated to accumulate 1225 events at the end of 3.78 years, resulting in premature termination (Fig

The drug hasn't been included in the 2024 National List of Health Services, and its inclusion in the coming years remains uncertain

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Among them, semaglutide was optimized to have a longer half-life in humans and a better resistance to Dipeptidyl Peptidase IV inhibitors than other GLP-1RAs 2

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