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A sweet, metallic, bitter or generally unusual taste is usually not dangerous on its own, but it should be monitored if it is persistent, severe, linked with poor fluid intake, or comes with symptoms such as vomiting, abdominal pain, dizziness, confusion or signs of high or low blood sugar

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On August 28, 2024, Eli Lilly and Company submitted anominationto request that its GLP-1 product, tirzepatide, be added to FDAs Demonstrable Difficulties for Compounding (DDC) lists.