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doi:10.1001/jamainternmed.2024.3579 Novikoff A, Mller TD
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The decrease in kidney function with an absence of albuminuria, hints of damage to the tubule-interstitial parts of the kidney, whilst a decrease in kidney function with presence of albuminuria, hints of damage to the glomeruli parts of the kidney [20]

By enabling efficient cytosolic delivery, they address a key remaining hurdle in GLP-1R-targeted intracellular therapy and significantly enhance the translational potential of nucleic acid and other intracellularly active therapeutics
