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Some feel better within days or weeks, while others take longer to recover [27]

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Adding tirzepatide to this mix requires careful attention

We therefore suggest monitoring drug levels at least at the start of cotreatment with GLP1RAs, especially in patients with kidney dysfunction who are at risk for drug accumulation to toxic levels

We moved from daily to weekly injections, saw the development of oral GLP-1 pills, and witnessed the rise of super-agonists like Ozempic, Wegovy, and Mounjaro, drugs that are fundamentally changing the landscape of obesity and diabetes management

Additionally, when GLP1R knockout mice were used to validate the impact of exenatide and liraglutide, no increase in calcitonin secretion or C-cell hyperplasia was observed