cagrilintide and semaglutide New in the August 14, 2025, issue of NEJM: ⁣ ⁣ Cagrilintide–Semaglutide for Overweight or Obesity (REDEFINE 1 phase 3a trial)⁣ ⁣ Cagrilintide– for Overweight Diabetes (REDEFINE 2 phase 3a trial)⁣ ⁣ Cagrilintide vs Semaglutide: Different Paths

Description

Requirements may include documentation of medical necessity, including BMI and comorbid conditions, proof or statement of a trial of lifestyle modification, or documentation that other medications were ineffective or contraindicated. That is also true of Aetnas prior authorization policy for Qsymia, which imposes quantity limits because phentermine is a controlled substance

Nusrat S, Borogovac A, George JN, Curtis BR, Reese JA

I'm not aware of any publications that actually report changes in pregnancy rates themselves, says Jessica Skelley, a pharmacist at Samford University in Birmingham, AL

But if you notice swelling of your face or have strong pain in your belly, you should see your healthcare provider right away

What to Avoid Eating While Taking Retatrutide High-fat and fried foods, sugary ultra-processed foods, large portions, carbonated beverages, and alcohol should be minimised or avoided as they worsen gastrointestinal side effects and destabilise blood glucose