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JAMA 303:14101418 Pratley RE, Nauck M, Bailey T et al (2010) Liraglutide vs sitagliptin for patients with type 2 diabetes who did not have adequate glycaemic control with metformin: a 26-week, randomised, parallel-group, open-label trial

One that political scientists Donald Stokes called Pasteur's Quadrant

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This is why many people see: Minimal weight loss early More consistent loss after dose increases Better results once appetite suppression stabilizes Patience during the early phase is important

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