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While we have developed new treatments for type 2 diabetes and obesity, such as glucagon-like peptide-1 (GLP-1) receptor agonists, their efficacy and accessibility are still limited

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Sabatine MS, Giugliano RP, Keech AC, Honarpour N, Wiviott SD, Murphy SA, Kuder JF, Wang H, Liu T, Wasserman SM, et al: Evolocumab and Clinical Outcomes in Patients with Cardiovascular Disease

Clinical trials that led to regulatory approval did not identify back pain as occurring at significantly higher rates in treatment groups compared to placebo