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Le GLP-1 (glucagon-like peptide-1) est une hormone naturellement produite par l'intestin qui joue un rle cl dans la rgulation de l'apptit, la signalisation de l'insuline et l'quilibre de la glycmie

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The first mechanism involves activation of cAMP and PI-3 K pathways via GLP-1R [54]

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Preclinical and early clinical data suggest this triple mechanism may reduce appetite and support metabolic function, though direct head-to-head comparisons with approved agents in humans are not yet available, and claims of superior potency remain unproven at this stage