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The GLP-1 analogs liraglutide and semaglutide reduce atherosclerosis in ApoE(-/-) and LDLr(-/-) mice by a mechanism that includes inflammatory pathways

Clinicians should emphasize that lifestyle changes, particularly dietary quality and eating patterns, remain important even when structured exercise is not feasible

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And it's a series of studies with different designs and populations to look, in randomized controlled trials that's the highest level evidence at what this drug would do for individuals with obesity, individuals with obesity who also had diabetes, what about if we add intensive lifestyle therapy to it, what would happen if we stopped the medication, what about individuals living with arthritis or with heart failure or heart disease

Discard any GLP-1 injection pen that has been frozen, even if it subsequently thaws

Did you have a history of gastroparesis
