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PIP3 formation activates Akt, which subsequently prevents Forkhead box O (FoxO)-1 from inhibiting the expression of POMC and from stimulating the expression of NPY and AgRP

10.1038/nn.4011 [DOI] [PMC free article] [PubMed] [Google Scholar] Gautron, L

People must wait 30 minutes before ingesting any food or drink

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