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10.1136/bmj.l4898 38 SunF.WuS.GuoS.YuK.YangZ.LiL.et al (2015)
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Studied doses typically range from 900 to 1,500 mg daily, divided into two or three doses to minimize gastrointestinal side effects, though it's important to note that berberine has poor and variable oral bioavailability

The disease, which is characterized by accumulation of liver fat, can go undiagnosed for years and is most definitively confirmed by an invasive liver biopsy

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Appetite suppression, blood glucose control and increased energy expenditure operate simultaneously, amplifying the weight-loss effect.
