retatrutide glp-1 gip glucagon triple agonist How Does Work? Doctor Explains Why It's So Effective Retatrutide for weight loss: Study

doi: 10.1002/jnr.21349 137 AdriaenssensAEBiggsEKDarwishTTadrossJSukthankarTGirishMet al

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If you needed split dosing or microdosing approaches to tolerate tirzepatide, moving to a compound with higher GI burden is a significant risk

otherwise, they can be categorized as low risk

These drugs by increasing insulin secretion and possibly, beta cell mass, decrease plasma glucose and lipids and have a secondary action to reduce food intake and bring about weight loss