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Comparing Mechanisms of Action While both GLP-1 and GLP-3 influence metabolic function, their specific mechanisms show important differences: Insulin Secretion GLP-1 powerfully stimulates insulin secretion in a glucose-dependent manner, meaning it only enhances insulin release when blood glucose is elevated

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Evaluation of treatment efficacy should not rely solely on weight reduction but also on endpoints such as fat mass (FM) and lean body mass (LBM)

Vrang N, Jelsing J, Simonsen L, Jensen AE, Thorup I, Soeborg H, et al

Ethics declarations Author taxonomy FA, PCS, MM Conceptualization

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