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Dopamine pathway proximity : GLP-1 receptors are expressed in brain regions involved in dopamine regulation, including the nucleus accumbens and ventral tegmental area

This rise can lead to better blood sugar control, reduced hunger, and more effective weight loss

N Engl J Med 2022;387:205-16.ArticlePubMed 29

Pfeffer MA, Claggett B, Diaz R, Dickstein K, Gerstein HC, Kber LV, Lawson FC, Ping L, Wei X, Lewis EF, et al

2.3 Outcomes The primary pharmacokinetic outcomes were the rate ( C max , t max ) and the extent (AUC) of drug absorption when an oral drug of interest was given concomitantly with versus without a GLP1RA

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