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Tirzepatides mechanism of action is to: lower food intake stimulate the release of insulin from the pancreas slow down the digestion process reduce the production of glucagon by the liver Together these mechanisms work to reduce appetite and cravings, improving weight loss results when following a diet plan

The source differs, but the mechanism and outcome are equivalent

Deciding which option best fits a specific patient's needs depends on careful consideration by healthcare practitioners incorporating information regarding any health concerns and tolerance of resulting symptoms related to drug usage

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Lead author Thomas Karagiannis of the Aristotle University of Thessaloniki told AFP that for the highest doses, "tirzepatide resulted in an average weight loss that was 5.7 kilograms (12.5 pounds) more than semaglutide"