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This primarily appears to be due to clinical results since GLP-1s lower A1C, reduce weight, improve cardiovascular outcomes, and potentially many other benefits

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Paired data where patients completed the questionnaire in both years were available in 31.4% (522/1665 [95% CIs 29.2-33.6%])

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Furthermore, the ad also provoked two senators, a Democrat (Dick Durbin, D-IL) and Republican (Roger Marshall, MD, R-KS), to write the FDA a letter expressing the legislators concerns about the lack of safety information in the ad threatening potential enforcement action