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In biochemical and preclinical research systems, GLP-RT interacts with three class B G protein-coupled receptors that regulate metabolic signaling networks: GLP-1R, GIPR, and GCGR

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Here, we investigated the effects of GLP-1 conjugated to estradiol (GE2) on metabolism, cognition, inflammation and neurogenesis in the hippocampus of middle-aged male and female rats fed a standard (SD) or Western (WD) diet

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Full trial results for humans are