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Unregulated or unsupervised use of semaglutide poses several long-term health risks, such as pancreatitis, gastrointestinal complications, and thyroid abnormalities

10.1016/j.clinthera.2016.03.039 [DOI] [PubMed] [Google Scholar] 25

Some patients plateau after 6-12 months at a new, lower weight

This treatment is safe for individuals without diabetes and is commonly prescribed for weight loss in non-diabetic patients

At the risk of being overexplanatory, how fast semaglutide works kind of depends on your definition of "works." The drug starts working as soon as you take it, but it can be days or weeks before you feel the effects (like appetite suppression)
