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Ideally, these discussions occur before therapy begins

45 Products that are a combination of a DPP-4 inhibitor and an SGLT2 inhibitor (sitagliptin/ertugliflozin, saxagliptin/dapagliflozin, and linagliptin/empagliflozin) may be used to further lower A1C and provide increased CV benefit in patients who are not meeting A1C goals on dual therapy

Results and discussion Peptide-oligourea hybrids design and functional assay Our peptideoligourea hybrids design started with GLP-1-NH 2 and the introduction of a glycine in position 2 of GLP-1 instead of alanine (GLP-1-G 2 , 1 ) as it is known to prevent DPP-4 degradation 31,32,33

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