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In addition, GLP-1 therapies may modify bile acid metabolism, which is known to shape microbial diversity and metabolic signaling pathways

Part of the increased risk is due to the role the gastrointestinal system plays in regulating blood sugar levels

PMID: 16 McIntyreRSSoczynskaJKChaDSWoldeyohannesHODaleRSAlsuwaidanMTet al

Cagrilintide and retatrutide are two investigational peptide-based medicines currently being studied for the treatment of obesity and related metabolic conditions
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A gap over 90 days between prescription fills marked the end of treatment, to account for immortal time bias [23]
