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In this experiment, in the obese mice group, the expression of muscle atrophy markers Atrogin-1 and MuRF-1 of C2C12 myotube cells increased, and the expression of myogenic differentiation markers (MyoD, Myogenin) and SIRT1 decreased

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[DOI] [PubMed] [Google Scholar] 135.Durell N, Franks R, Coon S, Cowart K, Carris NW

The rapid absorption kinetics support pramlintide's role as a mealtime peptide it reaches effective concentrations within minutes of injection, coinciding with the onset of gastric emptying and postprandial glucagon release