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The post hoc analysis found that tirzepatide at all doses investigated reduced the prevalence of metabolic syndrome related to cardiovascular risk factors more than placebo, semaglutide 1 mg, insulin degludec, and insulin glargine [117]

Frequently asked questions Is it better to take tirzepatide in the morning or at night

Semaglutide is a GLP-1R single agonist, similar to tirzepatide, that significantly improves hyperglycemia and obesity and has been approved by the FDA in 2021 as a weight loss drug for chronic weight management [18]

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Improves glucose-dependent insulin response

At 56 weeks, adults treated with liraglutide 3 mg achieved significantly greater mean weight loss of 5.9% compared with 2.0% with placebo ( P 10% weight loss: 25.2% in the liraglutide 3 mg group (compared to 6.7% with the placebo